Teams involved in this week’s League Cup semi-finals and April’s final will be allowed to make five substitutions instead of three, the English Football League (EFL) said on Monday.
This decision has come as the EFL look to ease the burden of fixture congestion.
The Premier League voted against allowing teams to make five substitutions per match this season, but the EFL said they had consulted with the four remaining clubs in the League Cup.
The clubs can also name nine substitutes on the bench.
Tottenham Hotspur host second-tier Brentford on Tuesday, while Manchester United take on Manchester City on Wednesday.
The League Cup final, which is usually held in February, was postponed to April 25 in the hope that fans will be able to attend.
Currently, fans are not allowed at the games due to COVID-19 restrictions.